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Tag: hopkinsmedicine.org

What’s in Your Wheat? Johns Hopkins Scientists Piece Together Genome of Most Common Bread Wheat

Johns Hopkins scientists report they have successfully used two separate gene technologies to assemble the most complete genome sequence to date of Triticum aestivum, the most common cultivated species of wheat used to make bread.
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Blueprint to Reduce Wasteful Blood Transfusions

By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. Publishing this week in JAMA Internal Medicine, the report also provides a how-to guide for launching a patient blood management program.
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Combination Low-Salt and Heart-Healthy “Dash” Diet as Effective as Drugs for Some Adults With High Blood Pressure

A study of more than 400 adults with prehypertension, or stage 1 high blood pressure, found that combining a low-salt diet with the heart-healthy DASH diet substantially lowers systolic blood pressure — the top number in a blood pressure test — especially in people with higher baseline systolic readings.
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‘Negative Emotions’ Linked to Higher Rates of Opioid Use in Sickle Cell Disease

In a small study using data from daily electronic patient diaries, Johns Hopkins researchers say they have found a link between negative emotions, such as sadness and anxiety, and higher opioid use in people with sickle cell disease whose pain levels were self-reported as relatively low.Source…

World AIDS Day: New Research and Experts Available from Johns Hopkins Medicine

World AIDS Day: New Research and Experts Available from Johns Hopkins MedicineSource…

Media Advisory: Johns Hopkins Commemorates World AIDS Day

To commemorate World AIDS Day this year, the Johns Hopkins Center for AIDS Research, which is affiliated with the Johns Hopkins University School of Medicine, is hosting the World AIDS Day Symposium. Topics of discussion include the state of HIV research during the past year and newly released research.
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2-Drug Combination May Boost Immunotherapy Responses in Lung Cancer Patients

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy. These so-called epigenetic therapy drugs, used together, achieved robust anti-tumor responses in human cancer cell lines and mice.
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Johns Hopkins Scientists Propose Efficiency ‘Rules’ for Enhancing Use of New Gene Editing Technology

Johns Hopkins scientists have developed a streamlined method and accompanying efficiency “rules” for introducing new DNA sequences into cells after using the gene-cutting tool known as CRISPR. The scientists say the method, which they based on tests with mouse embryos and thousands of human cells, could improve consistency and efficiency of genome editing.
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Study Suggests That Where Guidelines Disagree, Physicians’ Experiences With Their Patients, Family and Friends Shape Breast Cancer Screening Recommendations

Results of a national survey of more than 800 physicians suggest that their experiences with patients, family members and friends with breast cancer are linked with their recommendations for routine mammograms. Specifically, physicians who reported knowing at least one patient, family member or friend with a poor breast cancer prognosis and who had not been screened were more likely to recommend routine screening for their younger and older patients, age groups where routine screening is controversial.
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Combination Strategy Could Hold Promise for Ovarian Cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.
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